Developments in science and technology are forcing us to reconsider the priority of human needs in current theories of architecture and the built environment.. The present review aims to examine the existing literature systematically to explain the influence of the built environment on human experience by using approaches from neuroscience by examining the conceptualizations in the field. The study is conducted as a systematic qualitative review that analyzes and synthesizes the developing and emerging concepts that have appeared in the ever-evolving literature. The study concludes with an overall discussion about these concepts and their potential for providing further directions for future research.